From a CSV of contacts in August 2025 to a multi-channel, AI-personalized, Salesforce-aware commercial engine running today. This is the full picture — what we built, what broke, what we fixed, and where it's heading.
A month-by-month record of what shipped. The full chronological deep-dive lives at /timeline →
16-skill intelligence platform connecting to 8+ public APIs, commercial data sources, and outbound tools. From scrape to sent message — the full machine.
Explore the Backend →The operator cockpit at madescientificai.com. Accounts, campaigns, message generation, news intelligence, social listening — all in one dashboard the team uses daily.
Explore the UX →Two systems, one bridge. Joe's RAG + harness + knowledge graph on Made's side. BioCreative's data pipes and reference patterns on ours. Connected by sync functions, built on request.
Explore the Collaboration →Partnership-as-OS only works if people can operate it. Academy Starter Git live, 7 team members onboarding, Brian as standing resource. Everyone is a builder.
Explore Education →Frozen snapshot as of May 12, 2026. Honest status — green and yellow.
| System | Status | Cadence |
|---|---|---|
generate-outreach-message EF v93 | Live | On-demand + batch |
send-linkedin-messages cron | Live | Every 2h |
push-to-emailbison cron | Live | Every 2h |
sync-emailbison cron | Live | Every 6h |
sync-heyreach-every-6h cron | Live | Every 6h |
sync-heyreach-accepted cron | Live | Every 15 min |
News pipeline (made_sci scope) | Live | 2× daily |
| Social listening sync | Live | Every 4h |
heyreach-webhook EF | Schema bug — fix queued | Live events |
emailbison-webhook EF | Partial promote bug — fix queued | Live events |
| System | Status | Cadence |
|---|---|---|
| Salesforce sync (opps/leads/quotes) | Live | 2–3× daily |
| HubSpot contacts sync | Live | Nightly |
| Monday.com sync | Live | 3× daily |
| PandaDoc sync | Live | 3× daily |
| Salesforce proposal tri-sync | Live | 3× daily |
We keep the bug catalog public. These are known issues with fixes in progress:
This is a partnership document. Hiding the bugs would make it less useful.
We're both building toward the same architecture — Karpathy's LLM-OS pattern — from different angles.
Made's brain (Joe's side): Custom harness + agentic fleet, in-Postgres knowledge graph, hierarchical chunking, quality-scored re-ranking, multi-user session memory, Voyage embeddings.
BioCreative's brain: Hub data assets (17,300 companies, 265K contacts, 7,840 trials, 14K PIs, 2,946 grants, 2,919 patents) + knowledge graph (52K nodes, 31K relationships) + Karpathy-pattern memory hierarchy.
The bridge: Sync functions built on request. News and social listening already flowing every 4 hours. Trials, PIs, grants, patents standing by.
| Direction | What It Means |
|---|---|
| Stakeholder registration | Beyond therapeutic developers → financials, service providers, consultants, academic institutions |
| Cross-platform unified IDs | SFDC × HubSpot × Supabase × Bison × HeyReach contact resolution |
| Contextual engineers | Every team member up-skilled as an operator within their segment |
| Sub-agents | Specialized AI agents per department and workflow |
| GC Corp scale | Same platform pattern extended to the parent company's portfolio |